medicine
The recommended dose of Biphentin is 30 mg, 60 mg, 90 mg or 120 mg twice daily. The dose should be individualized according to patient response and tolerability. The first dose may be half the total daily dose if the medication is initiated in the morning, or one-third of the total daily dose if initiated in the afternoon or evening. Patients should be closely monitored for at least two weeks, or until significant clinical improvement occurs, when treatment is initiated and/or when a dosage change is made. If improvement is not apparent after five weeks at the maximum recommended dose, therapy with Biphentin should be reassessed.